Multiple rotational irregularities in an internal combustion engine are determined. An uneven running value of a currently-ignited combustion chamber in a logical ignition sequence of a plurality of combustion chambers immediately after a logically-preceding ignited combustion chamber is determined. The uneven running value determined for the logically-preceding ignited combustion chamber exceeds a specified threshold value and indicates a fault in the logically-preceding ignited combustion chamber. A compensation factor is determined that. A compensated uneven running value of the currently-ignited combustion chamber from the uneven running value of the currently-ignited combustion chamber and the compensation factor is determined. The compensated uneven running value of the currently-ignited combustion chamber is compared with the specified threshold value to determine whether the currently-ignited combustion chamber has a fault.