A computing system and a compressing method for neural network parameters are provided. In the method, multiple neural network parameters are obtained. The neural network parameters are used for a neural network algorithm. Every at least two neural network parameters are grouped into an encoding combination. The number of neural network parameters in each encoding combination is the same. The encoding combinations are compressed with the same compression target bit number. Each encoding combination is compressed independently. The compression target bit number is not larger than a bit number of each encoding combination. Thereby, the storage space can be saved and excessive power consumption for accessing the parameters can be prevented.