Techniques for mixed-precision data manipulation for neural network data computation are disclosed. A first left group comprising eight bytes of data and a first right group of eight bytes of data are obtained for computation using a processor. A second left group comprising eight bytes of data and a second right group of eight bytes of data are obtained. A sum of products is performed between the first left and right groups and the second left and right groups. The sum of products is performed on bytes of 8-bit integer data. A first result is based on a summation of eight values that are products of the first group's left eight bytes and the second group's left eight bytes. A second result is based on the summation of eight values that are products of the first group's left eight bytes and the second group's right eight bytes. Results are output.