An orientation control system for an agricultural implement includes a first sensor configured to be positioned at a left end portion of a frame. The first sensor is configured to emit a first output signal toward a soil surface and to receive a first return signal indicative of a first height of the left end portion. The orientation control system also includes a second sensor configured to be positioned at a right end portion of the frame. The second sensor is configured to emit a second output signal toward the soil surface and to receive a second return signal indicative of a second height of the right end portion. In addition, the orientation control system includes a controller configured to control first, second, and third actuators such that a difference between the first height and the second height is less than a threshold value.