A C-Arm X-ray imaging system using multiple pulsed X-ray sources in motion to perform efficient and ultrafast 3D radiography is presented. X-ray sources mounted on a structure in motion to form an array. X-ray sources move simultaneously relative to an object on a pre-defined arc track at a constant speed as a group. Each individual source can also move rapidly around its static position in a small distance. When a source has a speed that is equal to group speed but with opposite moving direction, the source at one C-arm end and X-ray flat panel detector at other C-arm end are activated through an external exposure control unit so that source stay momentarily standstill. The C-arm provides 3D X-ray scan imaging over a wide sweep angle and in different position by rotation. The X-ray image can be analyzed by an artificial intelligence module for real-time diagnosis.