- Patent Title: Meclozine derivatives and diclazuril derivatives for use in the prevention and/or the treatment of disorders associated to the inflammation induced by P. acnes
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Application No.: US16934055Application Date: 2020-07-21
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Publication No.: US11617748B2Publication Date: 2023-04-04
- Inventor: Nicolas Dupin , Vincent Calvez , Philippe Grange , Anne-Geneviève Marcelin
- Applicant: Universite Paris Descartes , Assistance Publique—Hopitaux de Paris , Institut National de la Sante et de la Recherche Medicale (INSERM) , Centre National de la Recherche Scientifique (CNRS) , Sorbonne Universite
- Applicant Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris
- Assignee: Universite Paris Descartes,Assistance Publique—Hopitaux de Paris,Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Sorbonne Universite
- Current Assignee: Universite Paris Descartes,Assistance Publique—Hopitaux de Paris,Institut National de la Sante et de la Recherche Medicale (INSERM),Centre National de la Recherche Scientifique (CNRS),Sorbonne Universite
- Current Assignee Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Erin M. Dunston
- Priority: EP16305912 20160713
- Main IPC: A61K31/495
- IPC: A61K31/495 ; A61P17/10 ; A61P17/06 ; A61K31/53 ; A61K45/06 ; A61K31/202 ; A61K31/203
Abstract:
The present invention relates to compounds of the following general formula (I) or (II) or a pharmaceutically acceptable salt and/or solvate thereof, for use in the prevention and/or the treatment of disorders associated to the inflammation induced by P. acnes, in particular in the prevention and/or the treatment of acne, psoriasis, chronic urticaria, urticaria pigmentosa, cutaneous autoinflammatory diseases, hidradenitis or atopic dermatis.
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