Invention Grant
- Patent Title: Pharmaceutical composition containing a tetrahydrofolic acid
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Application No.: US13721744Application Date: 2012-12-20
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Publication No.: US11617751B2Publication Date: 2023-04-04
- Inventor: Kristina King
- Applicant: Bayer Pharma AG
- Applicant Address: DE Berlin
- Assignee: Bayer Pharma AG
- Current Assignee: Bayer Pharma AG
- Current Assignee Address: DE Berlin
- Agency: Millen White Zelano and Branigan, PC
- Agent Csaba Henter
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/565 ; A61K31/00 ; A61K31/56 ; A61K31/4985 ; A61K31/567 ; B82Y5/00 ; A61K47/69

Abstract:
The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-methyl-(6S)-tetrahydrofolate; and at least one pharmaceutical acceptable excipient or carrier. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.
Public/Granted literature
- US20130178452A1 PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID Public/Granted day:2013-07-11
Information query
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