Invention Grant
- Patent Title: RP2 and RPGR vectors for treating X-linked retinitis pigmentosa
-
Application No.: US16854605Application Date: 2020-04-21
-
Publication No.: US11617801B2Publication Date: 2023-04-04
- Inventor: Zhijian Wu , Anand Swaroop , Suja Hiriyanna , Tiansen Li
- Applicant: The United States of Americans represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Bethesda
- Assignee: The United States of Americans represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of Americans represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethesda
- Agency: Leydig, Voit & Mayer
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K38/17 ; A61P27/02 ; C07K14/00 ; C07K14/47 ; C12N15/86 ; C12N15/864
Abstract:
Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
Public/Granted literature
- US20200289670A1 RP2 AND RPGR VECTORS FOR TREATING X-LINKED RETINITIS PIGMENTOSA Public/Granted day:2020-09-17
Information query
