Invention Grant
- Patent Title: Methods and compositions for treating a premature stop codon-mediated disorder
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Application No.: US17151126Application Date: 2021-01-16
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Publication No.: US11617802B2Publication Date: 2023-04-04
- Inventor: Jeffery M. Coller , Thomas Sweet , Harvey Lodish
- Applicant: CASE WESTERN RESERVE UNIVERSITY , WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
- Applicant Address: US OH Cleveland; US MA Cambridge
- Assignee: CASE WESTERN RESERVE UNIVERSITY,WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee: CASE WESTERN RESERVE UNIVERSITY,WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee Address: US OH Cleveland; US MA Cambridge
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61P25/08
Abstract:
Modified tRNAs can be used to express in a mammalian cell a functional gene product encoded by a gene containing a premature stop codon and/or to treat a disease mediated by a premature stop codon.
Public/Granted literature
- US20210299279A1 METHODS AND COMPOSITIONS FOR TREATING A PREMATURE STOP CODON-MEDIATED DISORDER Public/Granted day:2021-09-30
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