Invention Grant
- Patent Title: Inhibitors of APOL1 and methods of using same
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Application No.: US16717099Application Date: 2019-12-17
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Publication No.: US11618746B2Publication Date: 2023-04-04
- Inventor: Jingrong Cao , Jon H. Come , Leslie A. Dakin , Francois Denis , Warren A. Dorsch , Anne Fortier , Martine Hamel , Elaine B. Krueger , Brian Ledford , Suganthini S. Nanthakumar , Olivier Nicolas , Camil Sayegh , Timothy J. Senter , Tiansheng Wang , Michael Brodney , Kan-Nian Hu , Peter Rose , Kevin Gagnon , Yi Shi , Muna Shrestha , Ales Medek , Faith Witkos
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP.
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D405/14
Abstract:
The disclosure provides a compound of Formula (I), including deuterated derivatives, pharmaceutically acceptable salts, and solvates thereof, solid state forms of those compounds, compositions comprising those compounds and solid forms, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD).
Public/Granted literature
- US20200377479A1 INHIBITORS OF APOL1 AND METHODS OF USING SAME Public/Granted day:2020-12-03
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