Invention Grant
- Patent Title: Biomarkers of immune dysfunction in response to chronic stress, methods of use and diagnostic kits
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Application No.: US14121808Application Date: 2014-10-20
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Publication No.: US11618922B2Publication Date: 2023-04-04
- Inventor: Seid Muhie , Marti Jett , Rasha Hammamieh
- Applicant: The Government of the United States, As Represented by the Secretary of the Army
- Applicant Address: US MD Fort Detrick
- Assignee: The Government of the United States, As Represented by the Secretary of the Army
- Current Assignee: The Government of the United States, As Represented by the Secretary of the Army
- Current Assignee Address: US MD Fort Detrick
- Agency: McBee Moore & Vanik IP, LLC
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; C12Q1/6837 ; C12Q1/6809

Abstract:
Diagnostic biomarkers for diagnosing immune suppression/dysfunction. The diagnostic biomarkers are genes and/or transcripts that are up or down regulated compared to normal expression when a subject has been stressed either mentally and/or physically. The invention also relates to a method of detecting comprised or suppressed immune response in a subject by comparing certain diagnostic biomarkers in the subject to a control set of diagnostic biomarkers.
Public/Granted literature
- US20150051094A1 Biomarkers of immune dysfunction in response to chronic stress, methods of use and diagnostic kits Public/Granted day:2015-02-19
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