Invention Grant
- Patent Title: Methods and compositions relating to OPRM1 DNA methylation for personalized pain management
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Application No.: US16478706Application Date: 2018-01-19
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Publication No.: US11618924B2Publication Date: 2023-04-04
- Inventor: Vidya Chidambaran , Senthilkumar Sadhasivam , Hong Ji , Lisa Martin
- Applicant: CHILDREN'S HOSPITAL MEDICAL CENTER
- Applicant Address: US OH Cincinnati
- Assignee: CHILDREN'S HOSPITAL MEDICAL CENTER
- Current Assignee: CHILDREN'S HOSPITAL MEDICAL CENTER
- Current Assignee Address: US OH Cincinnati
- Agency: KDB Firm PLLC
- International Application: PCT/US2018/014405 WO 20180119
- International Announcement: WO2018/136728 WO 20180726
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883
Abstract:
The disclosure relates to methods for pain management in the perioperative context, particularly through the use of the DNA methylation status of the human OPRM1 gene as a biomarker for increased susceptibility to perioperative pain, and related methods and compositions.
Information query
