There is provided a method for generating a composite 2D interpretation image, comprising inputting each 2D medical image of a divided 3D image, into a 2D classifier trained on 2D images labelled with an indication of a visual finding, computing a respective explanation map for each respective 2D image, the respective explanation map including regions corresponding to corresponding regions of the respective 2D image, each respective region of the respective explanation map is associated with a computed explainable weight indicative of an influence of the respective corresponding region of the respective 2D image on the outcome of the 2D classifier fed the respective 2D image, and computing a composite 2D interpretation image comprising a respective aggregation weight for each respective region thereof, each respective aggregation weight computed by aggregating the explainable weights computed for the respective regions corresponding to the respective region of the composite 2D interpretation image.