The present disclose relates to a multiphase power converter and control circuit and control method thereof. The multiphase power converter comprises a plurality of power stage circuits, and each power stage circuit corresponds to one control circuit, each of the control circuit comprises a first port and a second port, wherein the first ports are connected to each other to receive centralized control signal, and the second port is configured to identify a phase sequence of each phase. The control circuit adjusts a working state of the current power stage circuit by gating corresponding pulse in the centralized control signal according to the centralized control signal and a current phase sequence, thereby realizing an interleaved control of the multiphase power converter. The control method realizes a uniform interleaving of control signals of each phase efficiently and simply, and further improves a power density of the multiphase power converter.