A method of an image sensor apparatus to be externally coupled to an external circuit through a circuit routing design includes: generating and outputting the clock signal and sensor data signals; and compensating an unbalance of the circuit routing design by automatically determining resultant delay amounts for the sensor data signals, applying a preliminary delay amount into the clock signal and applying the resultant delay amounts into the sensor data signals to generate and output delayed clock signal and delayed sensor data signals to the external circuit through the circuit routing design.