A staple cartridge comprising a cartridge body, staples, a first staple driver, a second staple driver, and a third staple driver is disclosed. The cartridge body comprises a knife slot and staple cavities defined in the cartridge body and arranged in an inner longitudinal row of staple cavities, a middle longitudinal row of staple cavities, and an outer longitudinal row of staple cavities on one side of the knife slot. The staples are removably stored within the staple cavities. The first staple driver is configured to eject a first quantity of staples from the staple cavities. The second staple driver is configured to eject a second quantity of staples from the staple cavities which is different than the first quantity of staples. The third staple driver is configured to eject a third quantity of staples that is the same as the first quantity of staples.