Implementations illustrated herein discloses a method of controlling drug titration to a patient, the method including receiving, using a processor, a sequence of depth images, each depth image including depth information for at least a portion of the patient, determining, using the processor, a sequence of physiological signals for the patient based on the sequence of depth images, analyzing, using the processor, the sequence of physiological signals for the patient to determine a change in a condition of the patient, and generating a signal to a drug infusion pump in response to determining the change in the condition of the patient.