Irregularly-shaped display panel and cutting method are provided. The display panel includes a display region and a non-display region surrounding the display region. The non-display region includes at least one irregularly-shaped boundary. The irregularly-shaped display panel further includes a substrate and the substrate includes a base substrate. The non-display region includes laser cutting trajectories. An orthographic projection of each of the laser cutting trajectories to the base substrate at least partially overlaps an orthographic projection of a corresponding irregularly-shaped boundary. Each of the laser cutting trajectories includes a cutting entry point and a cutting exit point at two ends thereof, and at least one of the cutting entry point and the cutting exit point does not overlap the orthographic projection of the corresponding irregularly-shaped boundary. The laser cutting trajectories are used as a laser cutting path.