Aerodynamic aquatic weed removal and decontamination devices and decontamination methods are disclosed. In an embodiment, the aerodynamic aquatic weed removal and decontamination device includes a boat body and a shore-based device for remotely controlling the boat body. The boat body includes a power unit, a weed removal and decontamination unit, a positioning system, an environment perception system, and a shipborne controller. The power unit includes an engine, a propeller connected to the engine, and a rudder servo motor configured to control a heading of the boat body. The weed removal and decontamination unit includes a mesh conveyor. The positioning system includes a positioner configured to obtain real-time location information and heading information of the boat body. The environment perception system includes a wind sensor and a visual sensor. The shipborne controller is configured to control a navigation state of the boat body.