Invention Grant
- Patent Title: Method for producing cartilage cells induced to be differentiated from stem cells
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Application No.: US16479079Application Date: 2018-01-19
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Publication No.: US11624056B2Publication Date: 2023-04-11
- Inventor: Ji Hyeon Ju , Yoo Jun Nam , Yeri Rim
- Applicant: YiPCELL Inc.
- Applicant Address: KR Seoul
- Assignee: YiPCELL Inc.
- Current Assignee: YiPCELL Inc.
- Current Assignee Address: KR Seoul
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: KR10-2017-0009015 20170119,KR10-2017-0009019 20170119
- International Application: PCT/KR2018/000903 WO 20180119
- International Announcement: WO2018/135902 WO 20180726
- Main IPC: C12N5/077
- IPC: C12N5/077 ; A61K35/32 ; C12N15/85

Abstract:
The present invention relates to a method for inducing differentiation, into chondrocytes, of cord blood mononuclear cell-derived induced pluripotent stem cells. In a case where a chondrogenic pellet produced by the method of the present invention is transplanted into a cartilage damage area in vivo, regeneration of cartilage can be effectively exhibited by differentiated chondrocytes. In such a case, an effective cartilage regeneration capacity can be exhibited as compared with a case where chondrocytes produced by differentiation induction with the addition of a recombinant growth factor are transplanted. Thus, the present invention can be usefully used for tissue engineering therapies.
Public/Granted literature
- US20190390167A1 METHOD FOR PRODUCING CARTILAGE CELLS INDUCED TO BE DIFFERENTIATED FROM STEM CELLS Public/Granted day:2019-12-26
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