Method, apparatus and system for real-time virtual network function orchestration in Real-time Cloud Infrastructure. The method comprises the step of updating and reporting CPU core RT performance; sending CPU and NUMA information; moving the IRQs from RT CPUset to Non-RT CPUset based on the CPU pool information response, and reporting the completion of IRQ clearance; moving the system tasks and OS background processes to Non-RT CPUset based on the CPU pool information response, and reporting the completion of system tasks clearance; clearing the known indeterminism sources based on the CPU pool information response, and reporting the completion of indeterminism sources clearance. The implementation of the method and apparatus improves that with support of NFV, edge cloud can speed new service deployment and achieve resource sharing among different services which allows operators to provision fewer resources.