The technology disclosed relates to inter-processor execution of configuration files on reconfigurable processors using smart network interface controller (SmartNIC) buffers. In particular, the technology disclosed relates to a runtime logic that is configured to execute configuration files that define applications and process application data for applications using a first reconfigurable processor and a second reconfigurable processor. The execution includes streaming configuration data in the configuration files and the application data between the first reconfigurable processor and the second reconfigurable processor using one or more SmartNIC buffers.