Systems, computer-implemented methods, and computer program products to facilitate automated generation of a machine learning pipeline based on a pipeline grammar are provided. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise a pipeline structure generator component that generates a machine learning pipeline structure based on a pipeline grammar. The computer executable components can further comprise a pipeline optimizer component that selects one or more machine learning modules that achieve a defined objective to instantiate a machine learning pipeline based on the machine learning pipeline structure.