A multi-zone climate control system for vehicles includes a front HVAC unit, a powered blower, and a heater core. The front HVAC unit is adapted to condition air provided to first and second front zones. The front HVAC unit further includes a cold air outlet connected to the powered blower. Cold air from the cold air outlet of the front HVAC unit passes through the powered blower and enters the heater core. The heater core is configured to control a temperature of conditioned air supplied to at least one rear zone of the passenger compartment.