A hydrophobic polyimide material and a preparation method thereof, and an organic electroluminescence light emitting diode are provided. The hydrophobic polyimide material includes organic/inorganic composite nanoparticles. The preparation method of the hydrophobic polyimide material includes steps: mixing polyamic acid solution and organic/inorganic composite nanoparticle solution evenly, and stirring to obtain solution of the hydrophobic polyimide material; coating the solution of the hydrophobic polyimide material on a surface of a substrate to obtain hydrophobic polyimide by baking and curing.