Invention Grant
- Patent Title: Method for diagnosing anomalies in the coagulation of blood
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Application No.: US15776203Application Date: 2016-11-15
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Publication No.: US11630101B2Publication Date: 2023-04-18
- Inventor: Christophe Nougier
- Applicant: Hospices Civils de Lyon
- Applicant Address: FR Lyons
- Assignee: Hospices Civils de Lyon
- Current Assignee: Hospices Civils de Lyon
- Current Assignee Address: FR Lyons
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: FR1560945 20151116
- International Application: PCT/EP2016/077722 WO 20161115
- International Announcement: WO2017/085058 WO 20170526
- Main IPC: G01N33/49
- IPC: G01N33/49 ; G01N27/07

Abstract:
The present invention relates to a method for diagnosing anomalies in the coagulation of blood, comprising the following successive steps: a) placing a sample of total blood in a holder containing two pairs of electrodes connected to an apparatus generating an electrical current; b) incubating this sample for 60 to 180 seconds in the presence of calcium; c) adding to this sample tissue factor in a concentration high enough to trigger the coagulation of the blood; d) measuring the impedance variation between the electrodes as a function of time, for a period comprised between 10 and 30 minutes from step (c), and generating a curve of the impedance values as a function of time; e) comparing the value of the area under the curve generated in step (d) with the value of an area under a reference curve.
Public/Granted literature
- US20200256847A1 METHOD FOR DIAGNOSING ANOMALIES IN THE COAGULATION BLOOD Public/Granted day:2020-08-13
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