Methods, apparatus, and processor-readable storage media for automatically remediating storage device issues using machine learning techniques are provided herein. An example computer-implemented method includes obtaining performance-related information pertaining to one or more storage devices; automatically determining one or more workflows to be executed in connection with remediating at least one issue attributed to at least a portion of the one or more storage devices, wherein determining the one or more workflows comprises applying one or more machine learning techniques to the obtained performance-related information; and performing one or more automated actions based at least in part on the one or more workflows.