A three-dimensional memory device includes an alternating stack of insulating layers and electrically conductive layers located over a substrate. Each electrically conductive layer within a subset of the electrically conductive layers includes a respective first metal layer containing an elemental metal and a respective first metal silicide layer containing a metal silicide of the elemental metal. Memory openings vertically extend through the alternating stack. Memory opening fill structures located within the memory openings can include a respective memory film and a respective vertical semiconductor channel.