Invention Grant
- Patent Title: Transcriptome-wide design of selective, bioactive small molecules targeting RNA
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Application No.: US16214327Application Date: 2018-12-10
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Publication No.: US11636918B2Publication Date: 2023-04-25
- Inventor: Matthew D. Disney , Sai Velagapudi
- Applicant: University of Florida Research Foundation, Incorporated , The Research Foundation for the State University of New York
- Applicant Address: US FL Gainesville; US NY Albany
- Assignee: University of Florida Research Foundation, Incorporated,The Research Foundation for the State University of New York
- Current Assignee: University of Florida Research Foundation, Incorporated,The Research Foundation for the State University of New York
- Current Assignee Address: US FL Gainesville; US NY Albany
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: G16B15/30
- IPC: G16B15/30 ; G16B15/00 ; G16B30/00 ; C07D235/18 ; C07D403/14 ; C07H15/04 ; G16B30/10 ; C07D235/20 ; C07H15/234 ; G01N33/53
Abstract:
Methods and computer systems are described herein for identifying small molecules that bind to selected RNA structural features (e.g., to RNA secondary structures). Also described are compounds and compositions that modulate RNA function and/or activity.
Public/Granted literature
- US20190156912A1 TRANSCRIPTOME-WIDE DESIGN OF SELECTIVE, BIOACTIVE SMALL MOLECULES TARGETING RNA Public/Granted day:2019-05-23
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