A method for securing a networked computer system executing an application includes identifying a vulnerable computer resource in the networked computer system, determining all computer resources in the networked computer system that are accessible from, or are accessed by, the vulnerable computer resource, and prioritizing implementation of a remediation action to secure the vulnerable computer resource if a vulnerability path extends from the vulnerable computer resource to a critical computer resource that contains sensitive information. The remediation action to secure the vulnerable computer resource is a safe remediation action that does not impact availability of the application executing on the networked computer system.