Various embodiments of a predictive fall event management system and a method of using such system are disclosed. The system includes a body-worn device and a controller operatively connected to the body-worn device. The controller is adapted to receive physiological data representative of a physiological characteristic of a wearer of the body-worn device over a monitoring time period; receive contextual data representative of context information of the wearer over the monitoring time period; and determine one or more future physiological states or contextual states based at least in part on one or more of the physiological data and the contextual data. The controller is further adapted to determine, for a future time, whether a fall condition is satisfied based upon the one or more future physiological states or contextual states and generate a fall prevention output responsive to satisfaction of the fall condition.