Invention Grant
- Patent Title: Substituted amino triazoles useful as chitinase inhibitors
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Application No.: US16929893Application Date: 2020-07-15
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Publication No.: US11638707B2Publication Date: 2023-05-02
- Inventor: Marzena Mazur , Gleb Andryianau , Lukasz Joachimiak , Wojciech Czestkowski , Michal Kowalski , Piotr Niedziejko , Sylwia Olejniczak , Krzysztof Matyszewski , Robert Koralewski , Jacek Olczak , Adam Golebiowski , Agnieszka Bartoszewicz
- Applicant: Molecure S.A.
- Applicant Address: PL Warsaw
- Assignee: Molecure S.A.
- Current Assignee: Molecure S.A.
- Current Assignee Address: PL Warsaw
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon; Laura A. Wzorek
- Priority: PL430586 20190715
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D413/14 ; A61K31/00 ; A61K31/5365 ; A61K31/454 ; A61K31/4545 ; A61K31/5355 ; A61K45/06 ; C07D498/04

Abstract:
Disclosed are amino triazole compounds of formula (I). These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
Public/Granted literature
- US20210015822A1 SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS Public/Granted day:2021-01-21
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