Invention Grant
- Patent Title: Ocular applications of matrix bound vesicles (MBVs)
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Application No.: US16610866Application Date: 2018-05-04
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Publication No.: US11638724B2Publication Date: 2023-05-02
- Inventor: Stephen F. Badylak , Anne E. Faust , George S. Hussey , Yolandi Van der Merwe , Michael Brandt Steketee
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2018/031190 WO 20180504
- International Announcement: WO2018/204848 WO 20181108
- Main IPC: A61K35/22
- IPC: A61K35/22 ; A61K9/00 ; A61K38/44 ; A61K45/06 ; A61K9/51 ; C12N15/113 ; A61P27/02 ; A61P27/06 ; A61K9/06
Abstract:
Methods are disclosed herein for increasing retinal ganglion cell survival in a subject in need thereof. These methods include selecting a subject in need of increased retinal ganglion cell survival and administering a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix (MBVs) to the subject.
Public/Granted literature
- US20210137988A1 OCULAR APPLICATIONS OF MATRIX BOUND VESICLES (MBVS) Public/Granted day:2021-05-13
Information query
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