Invention Grant
- Patent Title: Substituted chromanes, analogs thereof, and methods of use and synthesis
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Application No.: US16923843Application Date: 2020-07-08
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Publication No.: US11639340B2Publication Date: 2023-05-02
- Inventor: Karl A. Scheidt , Rick C. Betori , Benjamin R. McDonald
- Applicant: NORTHWESTERN UNIVERSITY
- Applicant Address: US IL Evanston
- Assignee: NORTHWESTERN UNIVERSITY
- Current Assignee: NORTHWESTERN UNIVERSITY
- Current Assignee Address: US IL Evanston
- Agency: Quarles & Brady LLP
- Main IPC: C07D311/58
- IPC: C07D311/58 ; C07D215/14 ; C07D215/58 ; C07D307/80 ; C07D311/92
Abstract:
Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.
Public/Granted literature
- US20210009547A1 SUBSTITUTED CHROMANES, ANALOGS THEREOF, AND METHODS OF USE AND SYNTHESIS Public/Granted day:2021-01-14
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