Invention Grant
- Patent Title: Crystal form of tipifarnib and method of treatment thereof
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Application No.: US17133508Application Date: 2020-12-23
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Publication No.: US11639341B2Publication Date: 2023-05-02
- Inventor: Xiaohong Sheng , Xiaoxia Sheng , Yanli Dai
- Applicant: Hangzhou SoliPharma Co., Ltd.
- Applicant Address: CN Zhejiang
- Assignee: Hangzhou SoliPharma Co., Ltd.
- Current Assignee: Hangzhou SoliPharma Co., Ltd.
- Current Assignee Address: CN Zhejiang
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C07D401/06
- IPC: C07D401/06

Abstract:
The present invention relates to novel crystal forms of tipifarnib. Compared with the prior art, the crystal forms of tipifarnib have advantages in crystallinity, hygroscopicity, morphology, form stability and chemical stability. The present invention also relates to the preparation methods of crystal forms of tipifarnib, pharmaceutical composition thereof and their use in preparation for treating and/or preventing abnormal cell growth diseases.
Public/Granted literature
- US20210214335A1 CRYSTAL FORM OF TIPIFARNIB AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF Public/Granted day:2021-07-15
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