Invention Grant
- Patent Title: Dihydrochromene derivatives
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Application No.: US16944482Application Date: 2020-07-31
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Publication No.: US11639357B2Publication Date: 2023-05-02
- Inventor: Hitoshi Ban , Seiji Kamioka , Yusuke Sawayama , Miki Hashizume
- Applicant: Sumitomo Pharma Co., Ltd.
- Applicant Address: JP Osaka
- Assignee: Sumitomo Pharma Co., Ltd.
- Current Assignee: Sumitomo Pharma Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JPJP2018-052971 20180320
- Main IPC: C07D491/20
- IPC: C07D491/20

Abstract:
The present invention relates to the compound of formula (I) wherein R1A, R1B, R1C, and R1D are hydrogen atom, etc., R2A and R2B are hydrogen atom, etc., R3A, R3B, R3C, and R3D are hydrogen atom, etc., L is bond, etc., V is C1-6 alkylene, Q is optionally-substituted imidazole, or a pharmaceutically acceptable salt thereof, as a novel anti-tumor agent that targets CSCs which are thought to be closely involved in the persistent proliferation of malignant tumor, metastasis or recurrence of cancer, and resistance to anti-tumor agents.
Public/Granted literature
- US20210002290A1 DIHYDROCHROMENE DERIVATIVES Public/Granted day:2021-01-07
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