Invention Grant
- Patent Title: Peptidylic inhibitors of nucleolin (NCL) targeting CAG-repeat RNA toxicity and methods for reducing polyQ-mediated toxicity in polyQ diseases
-
Application No.: US15046249Application Date: 2016-02-17
-
Publication No.: US11639371B2Publication Date: 2023-05-02
- Inventor: Ho Yin Edwin Chan , Jacky Chi-Ki Ngo , Qian Zhang
- Applicant: The Chinese University of Hong Kong
- Applicant Address: CN Shatin
- Assignee: The Chinese University of Hong Kong
- Current Assignee: The Chinese University of Hong Kong
- Current Assignee Address: CN Shatin
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/18 ; C07K14/00 ; C07K14/47 ; A61P25/28 ; A61K38/17
Abstract:
The present invention provides for a novel peptide and method for treating polyglutamine (polyQ) diseases. Also disclosed are related compositions and kits for therapeutic use in the treatment of polyQ diseases.
Public/Granted literature
- US20170233442A1 PEPTIDYLYIC INHIBITOR TARGETING CAG-REPEAT RNA TOXICITY IN POLYGLUTAMINE DISEASES Public/Granted day:2017-08-17
Information query
IPC分类:
