Invention Grant
- Patent Title: CD80 variant immunomodulatory proteins and uses thereof
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Application No.: US16493750Application Date: 2018-03-13
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Publication No.: US11639375B2Publication Date: 2023-05-02
- Inventor: Ryan Swanson , Michael Kornacker , Mark F. Maurer , Joseph L. Kuijper
- Applicant: Alpine Immune Sciences, Inc.
- Applicant Address: US WA Seattle
- Assignee: Alpine Immune Sciences, Inc.
- Current Assignee: Alpine Immune Sciences, Inc.
- Current Assignee Address: US WA Seattle
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2018/022270 WO 20180313
- International Announcement: WO2018/170026 WO 20180920
- Main IPC: C07K14/70
- IPC: C07K14/70 ; C07K14/705 ; A61P35/00 ; A61K38/17 ; G01N33/574 ; A61K38/00 ; A61K39/00

Abstract:
Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
Public/Granted literature
- US20210130436A1 CD80 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF Public/Granted day:2021-05-06
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