Invention Grant
- Patent Title: UDP-glycosyltransferases
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Application No.: US16624072Application Date: 2018-06-26
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Publication No.: US11639497B2Publication Date: 2023-05-02
- Inventor: Viktor Marius Boer , Johannes Gustaaf Ernst Van Leeuwen
- Applicant: DSM IP ASSETS B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: McBee Moore & Vanik IP, LLC
- Priority: EP17178168 20170627
- International Application: PCT/EP2018/067061 WO 20180626
- International Announcement: WO2019/002264 WO 20190103
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N9/10 ; A23K20/163 ; A23L29/30 ; A23L27/30 ; A23L2/60 ; C12N9/02 ; C12P19/56

Abstract:
The present disclosure relates a polypeptide having UGT activity, which polypeptide comprises an amino acid sequence which, when aligned with a polypeptide having UGT activity comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid corresponding to any of amino acids at positions 35, 189, 280, 284, 285, 334 or 373, said positions being defined with reference to SEQ ID NO: 2 and wherein the polypeptide has one or more modified properties as compared with a reference polypeptide having UGT activity. A polypeptide according to the disclosure may be used in a recombinant cell for the production of steviol or a steviol glycoside.
Public/Granted literature
- US20210147816A1 UDP-GLYCOSYLTRANSFERASES Public/Granted day:2021-05-20
Information query
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