A touch sensing device, a touch display panel and a touch display panel motherboard. The touch sensing device includes: a first substrate; a plurality of patterned electrodes; and at least two lead layers, each lead layer includes a plurality of electrode leads, the plurality of electrode leads have a one-to-one correspondence relationship with the plurality of patterned electrodes, and each of the plurality of electrode leads is electrically connected to a corresponding one of the plurality of patterned electrodes.