Systems and methods for prioritizing trailers can include receiving a list of trailers at a distribution center, determining, for each trailer, an aggregate inventory readiness date, and ranking, into a high priority list, one or more trailers of the trailers that contain high priority items. The method can also include ranking, into an inventory readiness date list, one or more trailers of the trailers that were not added to the high priority list based on the aggregate inventory readiness date of each trailer, selecting, from the inventory readiness date list, trailers having the same aggregate inventory readiness date, ranking those trailers into a store need list based on one or more of the trailers containing needed items. The method can also include generating a trailer unload prioritization list based on combining the high priority list, the inventory readiness date list, and the store need list, and outputting the list.