A detachable endoscope includes an insertion unit including an illuminating and image pickup unit, an operation unit configured to bendingly operate a front end of the insertion unit, and a detachable unit configured to detachably couple the insertion unit and the operation unit to each other, wherein the detachable unit includes: a first detachable module disposed at the insertion unit; and a second detachable module disposed at the operation unit, wherein the first detachable module includes: a first module main body disposed within a rear end of the insertion unit and having first, second, third and fourth rectilinear guide through-bores penetratingly formed longitudinally therein, and a central opening penetratingly formed at a center of the main body in a thickness direction of the main body.