Invention Grant
- Patent Title: Polymer-based macromolecular prodrugs
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Application No.: US17670218Application Date: 2022-02-11
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Publication No.: US11642414B2Publication Date: 2023-05-09
- Inventor: Michael Chorny , Ivan Alferiev , Garrett M. Brodeur
- Applicant: The Children's Hospital of Philadelphia
- Applicant Address: US PA Philadelphia
- Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee Address: US PA Philadelphia
- Agency: RatnerPrestia
- The original application number of the division: US16969790
- Main IPC: A61K47/60
- IPC: A61K47/60 ; A61K31/4745
Abstract:
Provided are macromolecular prodrugs in which camptothecin analogs are covalently bonded to polymers via ester bonds that are labile under physiological conditions. Also provided are methods of treating cancer, especially neuroblastoma with the macromolecular prodrugs.
Public/Granted literature
- US20220160886A1 POLYMER-BASED MACROMOLECULAR PRODRUGS Public/Granted day:2022-05-26
Information query
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