Invention Grant
- Patent Title: Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
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Application No.: US16575749Application Date: 2019-09-19
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Publication No.: US11642415B2Publication Date: 2023-05-09
- Inventor: Sebastian Stark , Thomas Knappe , Harald Rau , Nicola Bisek , Burkhardt Laufer , Samuel Weisbrod , Tobias Voigt
- Applicant: Ascendis Pharma A/S
- Applicant Address: DK Hellerup
- Assignee: Ascendis Pharma A/S
- Current Assignee: Ascendis Pharma A/S
- Current Assignee Address: DK Hellerup
- Agency: Armstrong Teasdale LLP
- Main IPC: A61K47/61
- IPC: A61K47/61 ; A61K47/69 ; A61K9/00 ; A61K39/395
Abstract:
The present invention relates to hydrogel prodrug compositions comprising cross-linked hyaluronic acid (HA), or a derivative or a salt thereof, wherein the cross-linker system comprises a biodegradable spacer, wherein the cross-linked HA comprises a conjugated drug-linker, and wherein the linker is capable of releasing the drug under physiological conditions. The present invention further relates to methods for preparing the hydrogel prodrug compositions. The present invention further relates to methods for treating an ocular condition using the hydrogel compositions.
Public/Granted literature
- US20200222547A1 HYDROGEL CROSS-LINKED HYALURONIC ACID PRODRUG COMPOSITIONS AND METHODS Public/Granted day:2020-07-16
Information query
IPC分类:
