The present disclosure relates to an anti-pinch control system. The anti-pinch control system includes a motor configured to generate driving force for moving a seat of a vehicle, a pressure sensor configured to detect a pressure applied to the seat, a current measurement sensor configured to measure an amount of current generated by the motor, a database unit configured to store data on an amount of current required to drive the seat that corresponds to the pressure detected by the pressure sensor, and a controller configured to vary an anti-pinch value of the seat based on data corresponding to the pressure applied to the seat.