Invention Grant
- Patent Title: Monoclonal antibody against Nav1.7
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Application No.: US17059886Application Date: 2019-05-30
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Publication No.: US11643458B2Publication Date: 2023-05-09
- Inventor: Tatsuya Takahashi , Mai Yoshikawa , Sosuke Yoneda , Junji Onoda , Etsuo Nakamura , Tsuguo Miyauchi , Toshiyuki Asaki , Erika Kasai
- Applicant: SHIONOGI & CO., LTD.
- Applicant Address: JP Osaka
- Assignee: SHIONOGI & CO., LTD.
- Current Assignee: SHIONOGI & CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP 2018104391 2018.05.31
- International Application: PCT/JP2019/021444 2019.05.30
- International Announcement: WO2019/230856A 2019.12.05
- Date entered country: 2020-11-30
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/46 ; C07H21/04 ; C12N5/02 ; C12N1/20 ; C12N15/00 ; C07K16/18 ; A61P29/00 ; A61K39/00
Abstract:
Objective of the present invention is to provide a novel monoclonal antibody against Nav1.7. The present invention discloses a monoclonal antibody against Nav1.7 or its antibody fragment, having specific six CDRs (CDR1 to CDR3 of a heavy chain and CDR1 to CDR3 of a light chain) or specific heavy/light chain variable regions. The monoclonal antibody and the like can be used for treating or preventing pain, pruritus and so on.
Public/Granted literature
- US20210221876A1 A MONOCLONAL ANTIBODY AGAINST NAV1.7 Public/Granted day:2021-07-22
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