Invention Grant
- Patent Title: Early detection of preliminary stages of testicular germ cell tumors
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Application No.: US16341383Application Date: 2017-11-02
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Publication No.: US11643690B2Publication Date: 2023-05-09
- Inventor: Meike Spiekermann , Nina Winter , Gazanfer Belge , Arlo Radtke
- Applicant: miRdetect GmbH
- Applicant Address: DE Breman
- Assignee: miRdetect GmbH
- Current Assignee: miRdetect GmbH
- Current Assignee Address: DE Bremen
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: EP 196813 2016.11.02
- International Application: PCT/EP2017/078079 2017.11.02
- International Announcement: WO2018/083186A 2018.05.11
- Date entered country: 2019-04-11
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886

Abstract:
The present invention relates to methods of detecting preliminary stages of testicular germ cell tumors, more particularly testicular intraepithelial neoplasia (TIN), in a subject and to the use of miR-371a-3p as a biomarker for the detection of TIN. It further relates to the use of miR-371a-3p-specific primers and/or miR-371a-3p-specific probes and of corresponding kits for the detection of TIN.
Public/Granted literature
- US20200056243A1 Early Detection of Preliminary Stages of Testicular Germ Cell Tumors Public/Granted day:2020-02-20
Information query
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