Real-time intervention of an industrial process can include searching for a batch of candidate configurations for use by the industrial process, the batch of candidate configurations searched for by performing a batch Bayesian optimization (BBO). The batch of candidate configurations is transmitted to the industrial process to use in running the industrial process. A result of the run is received from the industrial process. Using the result in the BBO, a next batch of candidate configurations is searched. Whether a stopping criterion is met is determined, based on the next batch of candidate configurations and by applying a function to a BBO acquisition score. Responsive to determining that the stopping criterion is met, searching for the next batch of candidates is terminated.