A computer system includes a processor and a prefetch engine. The processor is configured to generate a demand access stream. The prefetch engine is configured to generate a first prefetch request and a second prefetch request based on the demand access stream, to output the first prefetch request to a first translation lookaside buffer (TLB), and to output the second prefetch request to a second TLB that is different from the first TLB. The processor performs a first TLB lookup in the first TLB based on one of the demand access stream or the first prefetch request, and performs a second TLB lookup in the second TLB based on the second prefetch request.