Systems for distributed, event-based computation are provided. In various embodiments, the systems include a plurality of neurosynaptic processors and a network interconnecting the plurality of neurosynaptic processors. Each neurosynaptic processor includes a clock uncoupled from the clock of each other neurosynaptic processor. Each neurosynaptic processor is adapted to receive an input stream, the input stream comprising a plurality of inputs and a clock value associated with each of the plurality of inputs. Each neurosynaptic processor is adapted to compute, for each clock value, an output based on the inputs associated with that clock value. Each neurosynaptic processor is adapted to send to another of the plurality of neurosynaptic processors, via the network, the output and an associated clock value.